An Analysis of the Effects of Phenytoin in Treating Motion Sickness and the Effects of Motion Sickness on the Human Electroencephalogram

Author

Todd M. Banducci

Date of Award

12-1990

Document Type

Thesis

Degree Name

Master of Science

Department

Department of Electrical and Computer Engineering

First Advisor

Matthew Kabrisky, PhD

Abstract

This research had two goals: to continue the ongoing research at AFIT to determine the efficacy of the anticonvulsant drug phenytoin in combating the onset and progression of motion sickness; and to note whether or not there is a discernable similarity in the brains of the test subjects to indicate a common point of origin (epicenter) and propagation pattern of the effects of motion sickness in the brain. Eight male DOD personnel were used as subjects to complete twelve trials. Four subjects completed the phenytoin verses placebo double-blind crossover experiment. These four subjects experienced a 99% mean increase in their free-time-to-emesis and a 613% mean increase in their symptom-free-times, with one subject remaining asymptomatic throughout his phenytoin trial.

AFIT Designator

AFIT-GSO-ENG-90D-2

DTIC Accession Number

ADA230423

Comments

The author's Vita page is omitted

Recommended Citation

Banducci, Todd M., "An Analysis of the Effects of Phenytoin in Treating Motion Sickness and the Effects of Motion Sickness on the Human Electroencephalogram" (1990). Theses and Dissertations. 8069.
https://scholar.afit.edu/etd/8069